Introduction:The quest for precision in CRISPR-Cas9 gene editing takes a significant leap forward with the development of BreakTag, a method devised to enhance our understanding of DNA double-strand breaks (DSBs) induced by Cas9. This breakthrough, detailed in a...
Herpes simplex virus. Credit: CDC Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an...
Coinciding with the historic approval of Vertex and CRISPR Therapeutics’ Casgevy as the first CRISPR-based therapeutic, epigenetic editing, which targets parts of the genetic code beyond the DNA itself, is having a moment. One company is already in the clinic, and two...
CRISPR pioneer Jennifer Doudna, Ph.D., looks set to continue to push the boundaries of gene editing, as she announces plans to team up with life sciences giant Danaher to create a center focused on generating new therapies for rare and other diseases. The center,...
AAV gene therapy-based genome editing recovered myelination in human CMT1A patient nerve differentiated from iPS cells. Credit: Department of Neuropathology, TMDU In a study published in Communications Medicine, researchers from Tokyo Medical and Dental University...
