GENE & CELL THERAPY · CRO AND CDMO
Plasmid DNA, AAV, lentivirus and mRNA–LNP, from research-grade vectors to GMP manufacturing, with sites in Houston and Guangzhou.
2026 Frost & Sullivan Global Gene Therapy CRDMO Technology Innovation Leadership Award
CRO · For research teams
Custom AAV at Cell Culture, Small Animal and NHP grades, plus plasmid, lentivirus and mRNA–LNP. AAV from 7 business days.
CDMO · For clinical programs
Process and analytical development, GMP plasmid and AAV manufacturing, fill & finish and release testing.
3,400+
Pharma companies and research institutions
60+
Multinational companies
30+
Countries and regions
679
Publications citing PackGene vectors
Selected clients
Citations as of Oct 5, 2026.
RESEARCH SERVICES
Order online, or start from a service. Standard turnaround is shown on each card.
Custom packaging with 100+ capsid options, including AAV2, 5, 6, 8 and 9.
From 7 business daysResearch-grade plasmid preparation for transfection and packaging.
15 business daysGene-to-lentivirus packaging for your cell studies.
15 business daysCustom mRNA synthesis and LNP formulation.
12 business daysDesign and build your expression cassette in piVector.
About 1 weekReady-to-use vectors and reagent kits.
10 builds a month for $299/mo, or 30 builds for $999/mo. Any insert size, one flat rate. Save 20% with annual prepay.
DISCOVERY TO CLINIC
NHP-grade AAV is made with the same cell line, plasmid system and process as our GMP production, which lowers tech-transfer risk when your program moves into the clinic.
For in vitro and cell-based experiments.
From 15 business days
For mouse and other small-animal studies.
From 21 business days
For NHP and large-animal studies.
From 25 business days
For clinical trials.
GMP release in 6–10 months
Typical timeline for an AAV program. Your project plan depends on construct, scale and testing scope.
Teams that started with research-grade vectors and continued into CDMO with us include Source Bio, Navega and the Eye & ENT Hospital of Fudan University.
CDMO SERVICES
Process development, analytical development, GMP manufacturing and fill & finish for AAV and plasmid programs, run from sites in Houston and Guangzhou.
Facility tours and audits: BD@packgene.com
25+
IND clearances, NMPA and FDA
30+
Investigator-initiated trials supported
150+
GMP batches delivered
2×1017
vg per 200 L batch, at most
BUILT FOR CLINICAL SUPPLY
AAV clinical work is mainly Phase I/II; analytical and plasmid projects run through Phase III.
Depending on your strategy, the two sites act as backup capacity for each other or as tech-transfer partners.
CASE STUDY · OPHTHALMOLOGY
JWK001 for nAMD was the first AAV candidate made with a dual-plasmid system, so there were few precedents for its methods, release testing and stability studies.
Analytical method development and validation, release testing, stability testing and characterization for the CMC package.
China's NMPA approved the IND for JWK001 Injection on Feb 22, 2024.
DYNO FRONTIERS NETWORK PARTNER
Source: PackGene press release, Oct 5, 2026
PACKGENE TECHNOLOGY
Five platforms behind every project, from vector design to scalable manufacturing.
AAV PRODUCTION · TWO-PLASMID SYSTEM
DuoPack™
Two plasmids instead of three. Compared with triple transfection, DuoPack doubles titer and cuts production cost by about half.
AAV CELL LINE
piAlpha™
Our own HEK293 suspension cell line for high-yield, high-quality AAV that scales.
See the platformPLASMID DNA
piOmega™
Plasmid DNA yields up to 1 g/L, with ≥95% supercoiled.
See the platformAAV VARIANT SCREENING
piIcosa™
7-amino-acid insertion libraries built on AAV2, 5, 6, 8 or 9 capsids.
See the platformVECTOR DESIGN
piVector™
Design and build your expression cassette online, then order construction, plasmid or packaging.
Open piVectorINTELLECTUAL PROPERTY
12
Patent applications in China (7), under PCT (3) and in the U.S. (2), covering:
SCIENTIFIC RESOURCES
Peer-reviewed work by our team, the research that uses our vectors, and application notes you can download.
PUBLICATIONS BY OUR TEAM
NEWS & EVENTS
https://www.doi.org/10.4103/NRR.NRR-D-24-01067
https://www.doi.org/10.1002/advs.75325
https://www.doi.org/10.1002/fsn3.71734
START YOUR PROJECT
Or email info@packgene.com · Toll-free 1-866-491-7300
