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| Nov 06 | Stem cells can tailor their role in gene therapy based on the underlying disease, study suggests read more » |
| Nov 04 | HuidaGene Therapeutics Receives the First-Ever FDA Clearance of CRISPR/Cas13 RNA-Editing HG202 for Macular Degeneration read more » |
| Nov 01 | Navigating the RNA Lipid Nanoparticle Landscape read more » |
| Nov 06 | Hospital-Based CGT Production the Best Option for Patients read more » |
| Nov 06 | Research team discovers a new mechanism in cancer cell immune evasion read more » |
| Nov 05 | Notch Therapeutics Signals a New Era in CAR-T Therapies read more » |
| Nov 04 | What will it take to get miRNA therapies to market? | Nature Biotechnology read more » |
| Nov 01 | Direct RNA Sequencing Supports Novel Discoveries in RNA Biology read more » |
| Nov 01 | The Golden Age of Medicine: Advancements in Novel Modalities and Therapeutic Areas read more » |
| Nov 05 | Inhibition of GPX4 enhances CDK4/6 inhibitor and endocrine therapy activity in breast cancer read more » |
| Nov 05 | Expression and distribution of rAAV9 intrathecally administered in juvenile to adolescent mice read more » |
| Nov 03 | Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription read more » |
| Nov 01 | Development of compact transcriptional effectors using high-throughput measurements in diverse contexts read more » |
| Oct 25 | Adeno-Associated Virus Gene Transfer Ameliorates Progression of Skeletal Lesions in Mucopolysaccharidosis IVA Mice read more » |
| Oct 24 | Lentiviral Vector-Mediated Ex Vivo Hematopoietic Stem Cell Gene Therapy for Mucopolysaccharidosis IVA Murine Model read more » |
| Oct 04 | AAVolve: Concatenated long-read deep sequencing enables whole capsid tracking during shuffled AAV library selection read more » |
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PackGene Biotech is a world-leading CRO and CDMO, excelling in AAV vectors, mRNA, plasmid DNA, and lentiviral vector solutions. Our comprehensive offerings span from vector design and construction to AAV, lentivirus, and mRNA services. With a sharp focus on early-stage drug discovery, preclinical development, and cell and gene therapy trials, we deliver cost-effective, dependable, and scalable production solutions. Leveraging our groundbreaking π-alpha 293 AAV high-yield platform, we amplify AAV production by up to 10-fold, yielding up to 1e+17vg per batch to meet diverse commercial and clinical project needs. Moreover, our tailored mRNA and LNP products and services cater to every stage of drug and vaccine development, from research to GMP production, providing a seamless, end-to-end solution.
Related News
FDA Approves Autolus’ New CAR-T Therapy for Aggressive Blood Cancer
In a significant development for cancer treatment, the US Food and Drug Administration (FDA) has approved Autolus Therapeutics’ CAR-T cell therapy for adult patients with relapsed or treatment-resistant B cell precursor acute lymphoblastic leukemia (B-ALL). This...
Gene Therapy Discovery: Stem Cells Tailor Their Behavior to Specific Genetic Diseases
Researchers at the RCCS San Raffaele Scientific Institute in Milan have uncovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the specific genetic disease being treated, providing critical insights for advancing...
Research team discovers a new mechanism in cancer cell immune evasion
Graphical abstract. Credit: Cell (2024). DOI: 10.1016/j.cell.2024.09.048An international team led by Goethe University Frankfurt has identified an intracellular sensor that monitors the quality of so-called MHC-I molecules, which help the immune system recognize and...
Hospital-Based CGT Production the Best Option for Patients
Manufacturing cell and gene therapies at hospitals in dedicated, GMP-accredited facilities would overcome many of the technical and logistical challenges associated with decentralized production. So says Na Kyung Lee, PhD, from Sungkyunkwan University in Seoul, Korea,...
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