[2024/10/11] Gene and Cell Therapy- weekly digest from PackGene

Oct 11, 2024

Featured

Oct 09 A Philadelphia biotech designed a first-of-its-kind therapy for rare cancer: Now, it waits for patients read more »
Oct 08 2024 Nobel Prize in Medicine: Discovering the Secrets of microRNA in Gene Regulation read more »
Oct 07 U.S. duo wins Nobel Prize in medicine for discovery of microRNA and gene regulation breakthrough read more »
Oct 03 Ultragenyx Provides Update on Stage 1 Cohorts in Pivotal Phase 1/2/3 Cyprus2+ Study Evaluating UX701 Gene Therapy for the Treatment of Wilson Disease read more »
News
Oct 09 Cell and Gene Therapy in Parkinson's Disease Clinical Trial Pipeline Analysis Demonstrates 18+ Key Companies at the Horizon Expected to Transform the Treatment Paradigm, Assesses DelveInsight read more »
Oct 09 Purespring nabs $105M to take gene therapy into the clinic as IgAN field matures read more »
Oct 09 Novel gene therapy shows promise in targeting a mutation linked to epilepsy read more »
Oct 08 Jim Wilson secures $100M for global approach aimed at reviving gene therapy field read more »
Oct 07 Ambros, Ruvkun Win the Nobel Prize in Physiology or Medicine for microRNAs read more »
Oct 07 Harnessing natural killer T cells to advance cancer immunotherapy for solid tumors read more »
Oct 04 World-first therapy using donor cells sends autoimmune diseases into remission read more »
Articles
Oct 22 Microbiome-induced reprogramming in post-transcriptional landscape using nanopore direct RNA sequencing read more »
Oct 09 AAV-mediated combination gene therapy of inducible Caspase 9 and miR-199a-5p is therapeutic in hepatocellular carcinoma read more »
Oct 09 Bidirectional regulation of motor circuits using magnetogenetic gene therapy read more »
Oct 08 Improved influenza vaccine responses after expression of multiple viral glycoproteins from a single mRNA read more »
Oct 07 A CRISPR-based method for detecting mRNA in extracellular vesicles | Nature Biotechnology read more »
Oct 07 Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap read more »
Oct 06 GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency read more »
Oct 05 7559 TRIM21 Regulates Activation of ERK1/2 to Promote Growth and Drug Resistance in Pituitary Neuroendocrine Tumors read more »
Oct 04 The genomic and transcriptomic landscape of metastastic urothelial cancer read more »
Oct 01 Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection read more »
Oct 01 RNAs kiss and translate in germ granules | Nature Cell Biology read more »

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About PackGene

PackGene Biotech is a world-leading CRO and CDMO, excelling in AAV vectors, mRNA, plasmid DNA, and lentiviral vector solutions. Our comprehensive offerings span from vector design and construction to AAV, lentivirus, and mRNA services. With a sharp focus on early-stage drug discovery, preclinical development, and cell and gene therapy trials, we deliver cost-effective, dependable, and scalable production solutions. Leveraging our groundbreaking π-alpha 293 AAV high-yield platform, we amplify AAV production by up to 10-fold, yielding up to 1e+17vg per batch to meet diverse commercial and clinical project needs. Moreover, our tailored mRNA and LNP products and services cater to every stage of drug and vaccine development, from research to GMP production, providing a seamless, end-to-end solution.

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