Ferring Sees Historic Sales Boost from Bladder Cancer Gene Therapy

Apr 08 , 2025
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SAINT-PREX, Switzerland – April 9, 2025 – Ferring announced €2.3 billion in total revenues for 2024, a 7% increase year-over-year (AER) and 8% (CER), fueled by record-breaking Reproductive Medicine sales exceeding €1 billion and the first full year of U.S. sales for Adstiladrin, its gene therapy for bladder cancer. Adstiladrin (Nadofaragene firadenovec-vncg) is an FDA-approved gene therapy for high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ. It utilizes a non-replicating adenovirus vector to deliver a gene encoding human interferon alfa-2b, which is expressed locally in bladder cells to induce antitumor and immune-modulating effects. Administered via intravesical instillation every three months, it demonstrated a 51% complete response rate and a median response duration of 9.7 months in clinical trials. Common side effects include bladder discharge, fatigue, and urinary urgency. This therapy offers a non-surgical alternative for patients with limited treatment options.

The company achieved a 38% increase in operating profit to €192 million (AER, 43% CER) through strategic expense management and targeted investments in growth areas like Adstiladrin.

“2024 marked a year of significant progress, with strong performance in Reproductive Medicine and the emergence of Adstiladrin as a key growth driver,” stated Jean-Frédéric Paulsen, Chairman of the Board of Directors. “We are focused on maximizing our impact and delivering life-changing solutions to patients.”

https://www.ferring.com/ferring-achieved-record-sales-driven-by-reproductive-medicine-combined-with-the-emergence-of-adstiladrin/

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